Amycretin

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Product parameters

Product number

U6801

Molecular formula

C₃₄₃H₅₅₀N₉₄O₁₁₆

Product properties

White powder

CAS number

3005889-81-3

Synthesis method

Solid-phase chemical synthesis

Molecular weight

7846.6 ± 1.0

Amycretin is a novel single-molecule peptide drug that combines two covalently linked analogues of GLP-1 and amylin, creating a dual agonist of the GLP-1 and amylin receptors. Its structure enhances both appetite regulation and metabolic control. By activating GLP-1 pathways to reduce hunger and amylin pathways to slow gastric emptying and improve satiety, amycretin supports powerful, sustained weight reduction.

Research Applications:
  • Activates GLP-1 and amylin pathways to support metabolic regulation.
  • Helps reduce appetite and enhance satiety signals.
  • Slows gastric emptying to aid weight-management efforts.
  • Investigated for obesity and broader metabolic health applications.

 

Product number

U6801

Molecular formula

C₃₄₃H₅₅₀N₉₄O₁₁₆

Product properties

White powder

CAS number

3005889-81-3

Synthesis method

Solid-phase chemical synthesis

Molecular weight

7846.6 ± 1.0

COA

Items Standard Results
Appearance White or off-white powder White powder
Molecular Ion Mass 7846.6 ± 1.0 Conforms
Solubility Can be dissolved to 50 mg/ml in pure water Conforms
pH 7.0–9.0 8.1
Water Content (K.F) ≤ 8.0% 3.50%
Purity (UPLC) ≥ 95.0% 97.23%
Related Substance (UPLC) Total impurities ≤ 5.0% 2.77%
Largest individual impurity ≤2.0% 0.62%
Residual Solvent (GC) Methylene chloride ≤ 600 ppm N.D
Acetonitrile ≤ 410 ppm 166 ppm
Methanol ≤ 3000 ppm N.D
N,N-Dimethylformamide ≤ 880 ppm N.D
Isopropyl ether ≤ 5000 ppm N.D
Acid Group Ions (IC) TFA ≤ 0.1% N.D
PO₄³⁻ ≤ 0.1% N.D
 HAC ≤ 0.1% N.D
 Sodium Ion (IC) ≤ 4.0% 3.20%
Microbial Limits TAMC ≤ 1000 cfu/g Conforms
TYMC ≤ 100 cfu/g Conforms
Bacterial Endotoxins ≤ 10 EU/mg Conforms
Assay (UPLC) ≥ 90.0% 96.80%
Storage Keep in tight container, protect from light, store at a temperature of -20±5℃

HPLC

暂无

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