R&D-Driven Custom Peptide Solutions
R&D Capabilities
Utide’s R&D team offers deep practical expertise in peptide drug development, covering peptide synthesis, process development, and analytical characterization. With more than 20 years of hands‑on experience, the team excels at transforming complex peptide designs into robust, reproducible manufacturing processes.
The team specializes in process design for long‑chain and modified GLP‑1 class peptides, with established expertise in sequence optimization, long‑acting modification strategies, and process implementation—supporting technically demanding development‑stage programs.
Building on strong R&D foundations and deep peptide chemistry expertise, we translate development capabilities into flexible, project-specific custom peptide solutions.
Comprehensive Custom Peptide Synthesis Capabilities
From Sequence Design to Impurity Control — We Deliver More Than Peptides, We Deliver Solutions
Customized Amino Acid Sequences
Designing Challenging Sequences
Broad Length Coverage
Special and Non-Natural Building Blocks
Advanced Solutions for Difficult Sequences
Modification Versatility
Enabling Functionality Through Precise Structural Engineering
Peptide modification is critical for tuning biological activity, stability, and pharmacokinetic properties. We offer a comprehensive portfolio of standard and advanced modifications.
Terminal Modifications
Carrier proteins (KLH, BSA, OVA)
PEGylation (Polymers)
Click Chemistry Handles
Structural
Disulfide bonds (single/multi)
Lactam bridge cyclization
Hydrocarbon-stapled peptides
Functional
Phosphorylation (p-Ser, p-Thr)
Lipidation (palmitic acid)
Glycosylation
Methylation
Conjugation
Carrier proteins (KLH, BSA, OVA)
PEGylation (Polymers)
Click Chemistry Handles
Salt Form & Counter-Ion Control
Precision Down to the Final Chemical Form
Salt form selection plays a critical role in peptide stability, solubility, and experimental reproducibility. We provide precise control tailored to downstream applications.
- Common Salt Forms: TFA salts (default), Acetate salts, and Hydrochloride (HCl) salts.
- Desalting: Ultra-low residual TFA levels (<1%) achievable.
- Customized: Sodium, ammonium, and other customized salt forms available.
Impurity Profile & Quality Insight
The True Measure of Professional Peptide Manufacturing
Quality excellence extends beyond the main peak. Our impurity profiling strategy reflects a deep understanding of synthesis-related risks.
- Process-Related Impurity Control
Identification and control of deletion sequences, incomplete deprotection products, and oxidation-related impurities. - Water Content & Residual Solvent Testing
Strict monitoring of moisture levels and residual organic solvents to ensure stability and regulatory readiness. - Endotoxin Control
Endotoxin testing available for peptides intended for cell-based and animal studies, with levels as low as <0.01 EU/mg, ensuring biological assay integrity. achievable. - Customized: Sodium, ammonium, and other customized salt forms available.