Sermorelin

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Our products are intended for research use only. They are not permitted for any human or animal consumption.

Product parameters

Product number

U2901

Molecular formula

C₁₄₉H₂₄₆N₄₄O₄₂S

Product properties

White powder

CAS number

86168-78-7

Synthesis method

Solid-phase chemical synthesis

Molecular weight

3357.9 ± 1.0

Sermorelin is an analogue of the naturally occurring human Growth Hormone–Releasing Hormone (GHRH). By stimulating the pituitary gland to release growth hormone (GH), it increases plasma growth hormone levels. Sermorelin binds to the growth hormone–releasing hormone receptor and promotes growth hormone secretion by mimicking the mechanism of action of native Growth Hormone–Releasing Factor (GRF). Sermorelin is primarily used in the treatment of growth hormone deficiency or growth failure in children.

 

Research Applications:
– Growth hormone secretion stimulation
– Growth hormone deficiency diagnosis
– Pediatric GHD treatment
Product number

U2901

Molecular formula

C₁₄₉H₂₄₆N₄₄O₄₂S

Product properties

White powder

CAS number

86168-78-7

Synthesis method

Solid-phase chemical synthesis

Molecular weight

3357.9 ± 1.0

COA

Items Standard Results
Appearance White or off-white powder White powder
Molecular Ion Mass 3357.9±1.0 Conforms
Solubility Can be dissolved to 5 mg/ml in pure water Conforms
pH 4.0~7.0 4.8
Water Content (K.F) ≤ 8.0% 3.90%
Purity (UPLC) ≥ 99.0% 99.20%
Related Substance (UPLC) Total impurities ≤ 1.0% 0.80%
Related Substance (UPLC) Largest individual impurity ≤0.5% 0.33%
Residual Solvent (GC) Methylene chloride ≤ 600 ppm N.D
Acetonitrile ≤ 410 ppm 172 ppm
Methanol ≤ 3000 ppm N.D
N,N-Dimethylformamide ≤ 880 ppm N.D
Isopropyl ether ≤ 5000 ppm N.D
Acid Group Ions (IC) TFA ≤ 0.1% N.D
PO₄³⁻ ≤ 0.1% N.D
 HAC ≤ 10.0% 7.80%
Microbial Limits TAMC ≤ 1000 cfu/g Conforms
TYMC ≤ 100 cfu/g Conforms
Bacterial Endotoxins ≤ 10 EU/mg Conforms
Assay (UPLC) ≥ 95.0% 99.90%
Storage Keep in tight container, protect from light, store at a temperature of -20±5℃

HPLC

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