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| Product number | U3903 |
|---|---|
| Molecular formula | C₁₉₄H₃₁₂N₅₄O₅₉S₂ |
| Product properties | White powder |
| CAS number | 1415456-99-3 |
| Synthesis method | Solid-phase chemical synthesis |
| Molecular weight | 4409.069 |
Cagrilintide is a long-acting and stable analogue of amylin. Amylin is a naturally occurring peptide that regulates food intake and metabolism. By activating amylin receptors (AMYRs), it induces satiety and helps prevent overeating, thereby reducing energy intake. At the same time, it can increase energy metabolism and reduce adipose tissue mass.
| Product number | U3903 |
|---|---|
| Molecular formula | C₁₉₄H₃₁₂N₅₄O₅₉S₂ |
| Product properties | White powder |
| CAS number | 1415456-99-3 |
| Synthesis method | Solid-phase chemical synthesis |
| Molecular weight | 4409.069 |
| Tests | Acceptance Criteria | Results | |
| Solubility | Can be dissolved to 50 mg/ml in pure water | Confirms | |
| Molecular Ion Mass | 4409.1 ± 1.0 | Confirms | |
| Water Content (KF) | NMT 8.0% | 2.20% | |
| Purity (HPLC) | NLT 99.0% | 99.23% | |
| Related substances (HPLC) | The largest individual impurity test NMT 0.5% | 0.34% | |
| The total impurities test NMT 1.0% | 0.77% | ||
| Residual solvent (GC) | DCM | NMT 600 ppm | N.D |
| ACN | NMT 410 ppm | 122 ppm | |
| MetOH | NMT 3000 ppm | N.D | |
| DMF | NMT 880 ppm | N.D | |
| Isopropyl ether | NMT 5000 ppm | N.D | |
| Acid group ions (HPLC) | （TFA） | NMT 0.1% | N.D |
| （PO₄³⁻） | NMT 0.1% | N.D | |
| （HAC） | NMT 0.1% | N.D | |
| Microbial Limits | TAMC | ≤ 1000 cfu/g | Confirms |
| TYMC | ≤ 100 cfu/g | Confirms | |
| Escherichia Coil presence | Negative | Confirms | |
| Salmonella | Negative | Confirms | |
| P. Aeruginosa | Negative | Confirms | |
| Sodium Ion (IC) | ≤2.0% | 1.40% | |
| Bacterial Endotoxins | ≤ 10 EU/mg | Confirms | |
| Assay (UPLC) | ≥ 95.0% | 98.80% | |
| Storage | Keep in tight container, protect from light, store at a temperature of -20±5℃ | ||
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